» A novel approach to reduce oxidative stress at molecular and cellular level with applications in regenerative medicine

OBJECTIVES

RESULTS

OBJECTIVES

The main objective of the project was to investigate the anti-oxidant, protective and other effects of High-Density Green Photons (HDGP) on biological systems and the possible optical manipulations at different molecular and cellular levels.

Mitrica R, Popescu I, Paslaru L, Badila D, Polosan S, Cristache L, Ionescu E, Tataru C, Comorosan S. High-density green photons effects on NaCl solutions detected by red blood cells membranes. Digest Journal of Nanomaterials and Biostructures, Vol. 7, No. 1, January – March 2012, p. 227 – 235
Comorosan S, Polosan S, Popescu I, Paslaru L, Nastase A, Mitrica R, Ionescu E. Antioxidant effects induced in biological macromolecular systems by high density photons through localized excitations. Biochimica et Biophysica Acta (BBA) – Bioenergetics, 1817, 1, 2012.
Paslaru L, Nastase A, Stefan L, Florea R, Sorop A, Ionescu E, Popescu I, Comorasan S. Stimulatory and possible antioxidant effects of high density green photons (HDGP) on cellular systems. Journal of Medicine and Life, vol 7,issue 4, oct-dec 2014, pp 619-622.
Alexandru P, Paslaru L, Dima S, Nastase A, Stoichita L,Comorosan S, Popescu Functional characterization of 1.1B4 novel human insulin releasing cell line and effect of HDGP (High Density Green Photons) irradiation on beta pancreatic cells and human pancreatic islets. J. Transl. Med. Res 2016;21(3):183-192.