Home » Laboratories » F0. Experimental Surgery

The Surgical Experimental Laboratory and the Simulation Center is conceived for training residents, specialists and senior surgeons in the latest minimally invasive and open surgical techniques, continuing education for practicing surgeons, and providing core lab support for pre-clinical research. As a certified facility, we ensure all procedures are in compliance with international and national guidelines.

The experimental lab is a comprehensive resource for surgical learning with activities that support continuing medical education (CME) organizations and the biomedical industry.

The two operating rooms are configurable to handle up to 8 training stations. The lab includes three video stations for hands-on, basic and laparoscopic skills training.



Evaluation of new surgical techniques – Classical, minimally invasive, transplantation surgery and their applicability in human medicine – Conducting basic surgical techniques for residents of all surgical specialties;

Organize at least 6 courses of minimally invasive surgical techniques every year (basic and advanced techniques) – resident doctors, specialists, senior doctors;

Providing the possibility of live demonstrations on animal models for new surgical instruments and techniques belonging to companies seeking to market such equipment;

Perform minimally invasive surgical interventions in the live animal (the porcine model) of different complexity in order to standardize the technique for applications in human surgery.


Areas of Research:

Experimental Surgery & Biomedical Industry Research: Pioneers in Electrolytic Electroporation Research.

Training in surgery: Surgical Workshops – Intraoperative Liver Ultrasound , Liver Resections, Tumor Ablations, Basic Intermediate and Advanced LaparoscopicalSkills

Fully equipped surgical lab, including

  • 3 Laparoscopic towers with ENDOCAM Logic HD (Wolf) with Laparoscopic instrument systems
  • 6 Anesthesia machines for veterinary use
  • Extracorporeal circulation perfusion systems (Bio-Console®560 – Arcos perfusion System)
  • High Definition Gastrointestinal Endoscopy System (HD+ HiLine PENTAX Endoscopy System)
  • Electrosurgical Generator with Argon Plasma Coagulation and Waterjet Surgical Modules
  • Argon plasma coagulation Machine
  • Schiller Defibrilator ( Defigard 5000)
  • Hitachi Preirus Ultrasound machine.



Hepato-pancreatic Biliary Surgical School

The role of the Surgical Workshops is to improve surgical procedures in duration, quality and postoperative outcome.

So far we have organised more than 20 workshops in HBP Surgery branch, that includes Intraoperative Liver Ultrasound, and Ultrasound guided Liver Resections workshops with more than 200 trainees so far.

The Center for Experimental Surgery has been the key link for translating the results of in vivo animal studies so that it can be applied to humans in the future.

The Institute has a well-equipped experimental surgery center including a biobase, two operating theaters – one open surgery, and a laparoscopic surgery platform and microsurgical maneuvering equipment. Here, both research projects and training courses for students, residents, specialists and primary doctors in various surgical techniques are being carried out.


Our surgical team members have a range of 7 to 20+ surgical years experience and master a various range of general surgery techniques.


Pilot Study on Minimally Invasive, Non-Thermal Tissue Ablation with a Single Exponential Decay Electrolytic Electroporation Waveform.

Project Managers: Prof. Dr. Irinel Popescu & Prof.  Boris Rubinsky

Scientific Directors: Prof. Michael K. Stehling, Dr. Franco Lugnani, Dr. Dana Tomescu, Dr. Vlad Herlea, CSI Dr. Dima Simona


A new minimally invasive tissue ablation technique, that combines the biophysical processes of electroporation and electrolysis, is introduced. The technology employs electrode needles inserted in the target tissue to deliver an Electrolytic Electroporation Waveform (EEW) in the form of an exponential decay voltage, several tens of microsecond long. A case study in a large animal model demonstrates that clinically significant size lesions can be achieved with a single, milliseconds long EEW. Ablation with EEW has major advantages over the comparable tissue ablation techniques of electrolysis, reversible electroporation and irreversible electroporation. EEW is orders of magnitude faster than conventional electrolytic ablation. EEW does not require the use of muscle relaxant as irreversible electroporation and EEW does not require injection of drugs as reversible electroporation. This new technology is simple to use and may become an important addition to the minimally invasive surgery armamentarium.

J. Transl. Med. Res 2016;21(4):247-252 DOI: 10.21614/jtmr-21-4-98




The strategic goal is to create research cores with advanced technological facilities in the form of research platforms by associating preclinical research laboratories and clinical research centers within the Fundeni Clinical Institute in a unique entity.

The newly created structure provides logistical support for biomedical research through the coordination of studies, quality management, data monitoring, dissemination of good clinical practice, database management and data analysis. Infrastructure is also dedicated to the production of vectors for gene and cellular therapy, as well as for the acquisition of new agents with therapeutic potential in digestive affection.

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