» Coman Cristin

Coman Cristin

Senior Researcher (Veterinarian)

[email protected]

About CV Lista de publicatii stiintifice:

Coman Cristin, senior researcher, veterinarian, specialist in laboratory animal science and medicine, diploma awarded by the French Ministry of Education and obtained at the Ecole Veterinaire in Toulouse.

Lecturer at Spiru Haret University, Faculty of Veterinary Medicine – disciplines Deontology and professional ethics and Biology, breeding and pathology of laboratory animals.

Chairman of the National Committee for the Protection of Laboratory Animals.

Areas of expertise:

management of experimental animal studies;
designing the experimental part on animals in research projects;
creation and development of transgenic mice strains;
testing the biocompatibility of medical devices;
preclinical testing of pharmaceutical drugs safety;
laboratory animal health surveillance programs in accordance with EU and FELASA regulations and recommendations;
legislation and ethics in animal experimentation;
3R and animal welfare;
biology and pathology of laboratory animals;
choosing the animal model;
genetic and environmental factors that influence animal experiments;
principles of minimally invasive animal procedures;
anesthesia, analgesia and human euthanasia of laboratory animals;
reporting, classification of severity of procedures;
design and functionalization of spaces for breeding and experimentation on animals.

CV 2020 Europass (EN) – Coman Cristin

List of main publications

Published books:

Cotor G., Coman C.- Laboratory animals, Biological features, breeding, use – CD- ROM, Ed. Ergorom-Bucharest, 2004 (in romanian).
Coman Cristin – Mucosal lymphoid digestive system reactivity in SPF mice – Ed. ASDPI, Bucharest, 2006 (in romanian). .
Coman C., Savi G., Cotor G.,- Mouse as laboratory animal, Ed. Alt. Press Tour, Bucharest, 2008.
Cristin COMAN, Magda GONCIAROV, Bogdan MARINESCU – Ethical evaluation and authorization of projects using animals in experimental procedures, Ed Printech, Bucharesti, 2017.
Published article:

C Coman, E Vlase – Diets – Critic points for in vivo tests, a comparative analysis between natural and purified diets – Lucr.st.Med.Vet., Timisoara, vol. XLII, 235-241, 2010.
Bogdan Marinescu, Cristin Coman – Ethics in animal experimentation – Romanian Journal of Bioethics, vol 3, nr. 3, 96-103, 2010.
B Marinescu, Gheorghita Isvoranu, Carolina Constantin, C Coman, Sabina Zurac, C Caruntu, D Boda, Monica Neagu, Mihaela Calin – Experimental model of chemical carcinogenesis in mice – Rev.Rom.Med.Vet., vol. 20, nr.4: 97-105, 2010.
Carmen Cristina Surdu-Bob, Cristin Coman, Ana Calugaru, Lidia Cremer, Marius Badulescu, Ene Vlase – Implant microparticles – a new concept for non-invasive cancer therapy – Romanian Archives of Microbiology and Immunology, vol. 70, nr. 1: 38-42, 2011.
Stefan Bogdan, Andrei Seferian, Andreea Totoescu, Stefan Dumitrache-Rujinski, Mihai Ceausu, Cristin Coman, Carmen-Maria Ardelean, Maria Dorobantu, Miron Bogdan – Sildenafil Reduces Inflammation and Prevent Pulmonary Arterial Remodeling of the Monocrotalines-induced Disease in the Wistar Rats – Maedica/A Journal of Clinical Medicine, vol 7, No 2, 109-116, 2012.
C. Coman , Carmen Cristina Surdu-Bob, D. Turcu, E. Vlase, Mariana Oporanu , M. Badulescu – Clinical and microbiological evaluation of an experimental model of human osteomyelitis – Rev.Rom.Med.Vet., vol. 23, nr.2: 65 – 73, 2013.
C. Coman, C. Calin, I. Patrascu – Evaluation of a bone regeneration experimental model of the upper jaw rabbit – Rev.Rom.Med.Vet., vol. 25, nr.2: 17 – 22, 2015.
Cristin Coman, Carmen Cristina Surdu-Bob, Magda Gonciarov, Ene Vlase, Marius Badulescu – Radiological Assessment of an Experimental Model of Human Osteomyelitis in Rabbits – Agriculture and Agricultural Science Procedia 6 ( 2015 ) 299 – 304, “ST26733”, International Conference “Agriculture for Life, Life for Agriculture”, doi:10.1016/j.aaspro.2015.08.076, ISSN 2210 – 7843, 2015.
Magda Gonciarov, Cristin Coman – General Principles Concerning the Harmonization of Romanian Legislation with the European Union in the Field of Protection of Animals Used for Scientific Scope – Agriculture and Agricultural Science Procedia 6 ( 2015 ) 336 – 341, “ST26733”, International Conference “Agriculture for Life, Life for Agriculture”, doi:10.1016/j.aaspro.2015.08.076, ISSN 2210 – 7843, 2015.

10. Crina Stavaru, Adrian Onu, Emilia Lupulescu, Catalin Tucureanu, Orhan Rasid, Ene Vlase, Cristin Coman, Iuliana Caras, Alina Ghiorghisor, Laurentiu Berbecila, Vlad Tofan, Richard A. Bowen, Nicole Marlenee, Airn Hartwig, Helle Bielefeldt- Ohmann, Susan L. Baldwin, Neal Van Hoeven,Thomas S. Vedvick, Chuong Huynh,Michael K. O’Hara,Diana L. Noah&Christopher B. Fox – Technology Transfer of Oil-in-Water Emulsion Adjuvant Manufacturing for Pandemic Influenza Vaccine Production in Romania: Preclinical Evaluation of Split Virion Inactivated H5N1 Vaccine with Adjuvant – Human Vaccines & Immunotherapeutics, DOI:10.1080/21645515.2015.1111495, ISSN 2164 -5515, 2015, 2016 Apr 2;12(4):1009-26, 2015

11. Raluca Elena Sandu, Adriana Uzoni, Cristin Coman, Aurel Popa-Wagner- Cerebral ischemia in the aged. Limited anti-inflammatory efficacy of the indomethacin treatment – Rom J Morphol Embryol, 56(3):1111–1117, 2015.

Carmen Cristina Surdu-Bob, Cristin Coman, Florica Barbuceanu, Danut Turcu, Nicolae Bercaru, Marius Badulescu – The influence of foreign body surface area on the outcome of chronic osteomyelitis – Medical Engineering and Physics, 2016, 38 870–876, http://dx.doi.org/10.1016/j.medengphy.2016.04.027, 2016.
Sergiu Cecoltan, Izabela Cristina Stancu, Diana Maria Dragusin, Andrada Serafim, Adriana Lungu, Catalin Tucurean, Iuliana Caras, Vlad Tofan, Aurora Salageanu, Eugeniu Vasile, Romain Mallet, Daniel Chappard, Cristin Coman, Mircea Istodorescu, Horia Iovu – Nanocomposite Particles with Improved Microstructure for 3D Culture Systems and Bone Regeneration – Journal of Materials Science: Materials

in Medicine, October 2017, 28:153, https://doi.org/10.1007/s10856-017-5966-8, 2017.

14. Cristin Coman, Ene Vlase – Formulation, preparation and chemical analysis of purified diets for laboratory mice and rats – Scientific Works. C Series. Veterinary Medicine, vol. LXIII (1): 149 – 154, 2017.

15. Cristin Coman – Development of zoonosis vaccines – Infectio.ro, vol 54 (2): 8-12, 2018.

16. Bogdan Sevastre, Alexandra I. Blidaru, Orsolya Sárpataki, Ioan Marcus and Cristin Coman – Retrospective Assessment of Animals Experimentation Projects in Romania – A Critical Analysis of Non-Technical Summaries -Bulletin Of University Of Agricultural Sciences and Veterinary Medicine Cluj-Napoca Veterinary Medicine vol 75 (2):190-195, 2018.

17. Aurel Popa-Wagner, Raluca E. Sandu, Coman Cristin, Adriana Uzoni, Kevin A. Welle, Jennifer R. Hryhorenko and Sina Ghaemmaghami – Increased Degradation Rates in the Components of the Mitochondrial Oxidative Phosphorylation Chain in the Cerebellum of Old Mice – Frontiers in Aging Neuroscience, 16 February 2018 | https://doi.org/10.3389/fnagi.2018.00032, 10:32, 2018.

18. Cristin Coman, Carmen Cristina Surdu-Bob, Florica Barbuceanu, Ene Vlase, Marius Badulescu – Histological assessment of an experimental model of human osteomyelitis in rabbits – “Agriculture for Life, Life for Agriculture” Conference Proceedings, vol 1:1, 432-437, doi: https://doi.org/10.2478/alife-2018-0065, 2018.

19.Carmen C. Surdu-Bob, Ene Vlase, Florica Barbuceanu, Danut Turcu, Mariana Coman, Marius Badulescu, Mariana Oporanu, Cristin Coman – Copper Bead Therapy in Severe Bone Infection: A Rabbit Tibial Model – Vet Comp Orthop Traumatol 2019;32:41–50, doi: https://doi.org/10.1055/s-0038-1676292 , 2019.

20. Marta Bottagisio, Cristin Coman, Arianna B. Lovati – Animal models of orthopaedic infections. A review of rabbit models used to induce long bone bacterial infections – Journal of Medical Microbiology, 15 march 2019, doi: 10.1099/jmm.0.000952, 2019.

21. I.S. Coman, C.G. Florea, Elena-Violeta Coman, D. Gheorghiţă, C. Coman, Angelica Dinu, Sabina Gabriela Ciuvică-Tănăsescu, C.D. Lupaşcu, Corina-Veronica Lupaşcu- Ursulescu, C.D. Badiu, V.T. Grigorean, M. Beuran – Dynamics of Clinical and Biological Elements in Mechanical Bowel Obstructions – Experimental Study on Laboratory Animals – Med. Surg. J. – Rev. Med. Chir. Soc. Med. Nat., Iaşi, 123, 1:116-131, 2019.

22. Cristin Coman, Teodoru Soare, Diana Istrate, Andrei Stoian, Diana Ancuța, Jasmina Manolescu – Evaluation of Alternative Routes of Intravenous Administration to the Method of Administration Substances by Penile Vein in the in vivo Antigenicity Test in Guinea Pigs – Scientific Works. C Series. Veterinary Medicine, vol. LXV (1): 128- 137, 2019.

23. Ionuţ Simion Coman, Costin George Florea, Daniel Gheorghiţă, Cristin Coman, Angelica-Iulica Dinu, Elena-Violeta Coman, Vlad Andrei Porojan, Oana-Ilona David, Ştefan Iulian Bedereag, Roxana Corina Sfetea, Sabina Gabriela Ciuvică-Tănăsescu, Gabriel Petre Gorecki, Valentin Titus Grigorean, Mircea Beuran – Histopathological elements analyzed in dynamics in mechanical bowel obstructions – experimental study on laboratory animals – Rom J Morphol Embryol, 60(2):589–599, 2019 .

24. I. Dorobanţu, L. Neagu, R. D. Stoica, C. C. Mustăciosu, C. Coman, D. Ancuţa – Evaluation of kinetic and thermodynamic parameters of the nanoimmunosorbent Sio2-Anti Dicamba antibody-dicamba-alkaline phosphatase antigen system in nanoelisa technique for assay of dicamba herbicide in environmental samples – Romanian Journal Of Physics 65, 701, 2020.